The Role of Oral and Dental Foci in Systemic Diseases

This research was originally published in 2020 by Nelli Yildirimyan, DDS. 

We have curated this article as a reference point for The Larkin Protocol.


Kidney Disease

Chronic kidney disease (CKD) is defined as reduced kidney function lasting longer than 3 months, and it is a major global health burden. In its early stages, CKD is frequently asymptomatic, but it presents with increased morbidity and mortality when kidney function becomes severely compromised. [37]


Patients with CKD commonly present with poor oral health and have a high prevalence for oral infections. [2, 38] This may lead to systemic inflammation, infection, protein wasting, and, as previously mentioned, atherosclerotic lesions

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