This research was originally published in 2020 by Nelli Yildirimyan, DDS.
We have curated this article as a reference point for The Larkin Protocol.
Chronic kidney disease (CKD) is defined as reduced kidney function lasting longer than 3 months, and it is a major global health burden. In its early stages, CKD is frequently asymptomatic, but it presents with increased morbidity and mortality when kidney function becomes severely compromised. 
Patients with CKD commonly present with poor oral health and have a high prevalence for oral infections. [2, 38] This may lead to systemic inflammation, infection, protein wasting, and, as previously mentioned, atherosclerotic lesions